A Leading Global Manufacturer of PQQ

Featuring PureQQ®: The PQQ Brand of Choice

We produce and supply PureQQ®, a pure Pyrroloquinoline Quinone product with a patented crystal form that the FDA has affirmed as GRAS (Generally Recognized As Safe). Our proprietary manufacturing processes ensure that our supply of PQQ powder is of the highest quality and availability, while also offering the greatest cost-efficiency.
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Due to differences in national and regional regulations, please contact info@howtiangroup.com for inquiries regarding compliance and marketability of PureQQ® in your region.

What is PQQ (Pyrroloquinoline Quinone)?

The “Best Kept Secret” in Nutritional Supplements

Pyrroloquinoline Quinone is a supplement that has been shown to have remarkable health benefits including brain health, cardiac function, and liver support. This vitamin-like micronutrient is also widely found in nature — in soil, plants, fruits, and animals. Foods that are rich in PQQ include celery, parsley, kiwi, papaya, spinach, beans, and potatoes. Dietary supplements are a convenient way to ensure a recommended daily intake. PQQ is an essential nutrient for a healthy mind, heart, and body, and is commonly used for anti-aging protection.

Benefits of PQQ

Brain Health

PQQ enhances cognitive function and improves short-term memory. It can help the brain to prevent memory loss and cognitive decline due to age and neurodegenerative disorders. With its ability to restore damaged brain and nerve cells, it has also been shown to promote recovery in cases of stroke and cerebral infarction.

Cardiovascular Function

PQQ improves blood circulation and cardiac function, supporting energy production in the heart and providing powerful antioxidant protection.  Studies indicate that PQQ can also promote recovery from heart attacks and reduction of infarct size.

Liver Support

PQQ aids the liver with fat metabolism to break down more fats and convert into greater energy output. Studies show it may also reverse acute and chronic liver injury, including damage from fatty liver disease.

Energy Production

In addition to supporting your vital organs, PQQ can augment and sustain higher levels of natural energy production at the cellular level. It is ideal as a sports supplement for athletes seeking natural alternatives to boost performance.

Skin Rejuvenation

Perhaps the most unique and unexpected benefit of PQQ is its use for cosmetic and skincare applications. It rejuvenates your skin cells and rebuilds healthy tissue for thicker skin, while reducing wrinkles and skin pigmentation. PQQ can be effective as anti-aging prevention not just for your brain, heart and liver, but also as a cosmetic anti-aging treatment for your skin.

Uses and Applications of PQQ

Brain Supplement

  • Enhances short-term memory, focus and recall
  • Prevents cognitive decline (memory loss, learning difficulty, etc.) due to age, stroke or neurodegenerative disorders
  • Protects and restores damaged brain and nerve cells
Heart Supplement

  • Stimulates mitochondrial growth and replication to support energy (ATP) production
  • Provides powerful antioxidant protection from damaging free radicals
Liver Supplement

  • Rescues acute and chronic liver injury
  • Suppresses Liver Fibrogenesis
Anti-aging Skin Supplement

  • Antioxidant protection and mitochondrial support for skin cells
  • Rebuild healthy tissue for thicker skin, reduce wrinkles and pigmentation
  • Improve skin moisture balance
  • A uniquely differentiated ingredient for cosmetic and anti-aging products

How Does PQQ Work?

Mitochondrial Growth & ATP Production

Mitochondria are the powerhouses of the cell and produce the vast majority of all cellular energy (ATP). PQQ activates a key transcription factor protein (CREB) and directly stimulates Mitochondrial Biogenesis, which is the growth and replication of new mitochondria. Stronger mitochondria, and more of them, produce more cellular ATP and thereby, users of PQQ may feel higher levels of natural energy.

Powerful Antioxidant Protection

Antioxidants protect your cells from damage inflicted by harmful molecules called free radicals. PQQ is an extremely potent antioxidant and is approximately 100 times more effective than Vitamin C at reducing these free radicals. A continuous supply of PQQ provides long-lasting protection and promotes the longevity of your heart, brain, liver and other organs rich in mitochondria.

Nerve Cells Support

Nerve Growth Factor (NGF) is a small protein that plays a critical role in the growth, development and maintenance of neurons. PQQ has been found to promote NGF production, with one study showing as much as a 40x increase. Increased levels of NGF help to maintain the health of the brain and peripheral nerves while also stimulating nerve regeneration. This promotes more mental energy, greater focus, and better short-term memory.

Dosage & Recommended Dietary Allowance (RDA)

PQQ supplements are most commonly sold at 10mg, 20mg and 40mg doses. For new users of such supplements, it is recommended to start at a dose of 10-20mg per day. Monitor the effects and adjust the dosage accordingly over time.

Chemical Details

Name: Pyrroloquinoline Quinone Disodium Salt

Molecular Formula: C14H4N2Na2O8

Molecular Weight: 374.17

CAS Number: 122628-50-6

Appearance: Reddish brown powder

Melting Point: >300 Degrees Celsius

Solubility: Water-soluble (3 g/L at 25 Degrees Celsius)

Stability: Stable for at least 36 months

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